The clinically-proven digital psychological therapy for patients with depression

deprexis® is a therapeutic support program available online.

Based on the proven principles of cognitive-behavioural therapy and other approaches such as positive psychology, deprexis® has demonstrated its efficacy and safety2-14.

What is deprexis®?

10 modules tailored to your needs and preferences

Based on the answers you choose, deprexis® individualises its approach according to predefined algorithms and build your own course of chats adapted to your situation*.

Self-assessment of mood and severity of depression

On a regular basis, deprexis® invites you to assess your mood and the severity of your depression so that you can monitor your progress.

Exercises and summary sheets

Throughout the program, deprexis® offers exercises and summary sheets that can be used on a daily basis to help you cope with your depression.

Daily support

If you wish, deprexis® can send you a daily support by text message or e-mail.

deprexis interface shown on several devices

In what way can digital therapy be adapted to treat depression?

There are still many difficulties in accessing optimal treatment for depression. They may be geographical or financial, linked to the lack of availability of psychiatrists and psychologists or to the fear of being stigmatised. Many patients also face long waiting times for access to psychotherapy.

Thanks to the flexibility and confidentiality of its online access, deprexis® allows you to access effective therapy, when you need it and regardless of the other treatments you are receiving for your depression1.

A crowded GP surgery waiting room

Are you a healthcare professional?

deprexis® has been studied in 12 randomised controlled trials in the most common care situations2-14.

Find out more about how deprexis was developed, how it works and whats benefits it can bring to your patients in your dedicated section.

A GP talking to his patient

deprexis® has proven its efficacy:



evaluating the efficacy and safety of deprexis® in the most common care situations2



included in clinical studies evaluating the efficacy of deprexis®2


+ 10


of clinical research consolidating the proof of efficacy of deprexis®


+ 80


of patients in a study reported that deprexis® was helpful3


*Depending on your choices, deprexis® may offer you a selection of chats from the twelve available.

**RCTs = Randomized Controlled Studies


Intended use:
deprexis® is intended to provide therapeutic methods and exercises based on evidence-based psychological and psychotherapeutic therapies for patients with unipolar depression or depressive disorders, to help them managing their depression or depressive disorder. deprexis is intended as a self-application supplemental to care-as-usual for patients 18 years of age or older. deprexis can be used for a period of 90 days. deprexis is neither intended to replace treatment provided by a health care provider nor to provide information which is used to take decisions with diagnosis or therapeutic purposes.


deprexis® should not be used by patients with bipolar disorder, psychotic disorder (e.g. schizophrenia) or by patients with suicidal risk.


Frequency of use:
Experience has shown that deprexis should ideally be used 1-2 times a week for at least half an hour for each session.


Read Instructions For Use carefully and follow its instructions. Available on


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